On March 16. Prof.Dr.-Ing. Sabine Roller and Dr. Jörg Bernsdorf presentet the research activities of the GRS lab Applied Supercomputing in Engineering at the 12th Teraflop Workshop at the HLRS Stuttgart, Germany. Prof. Roller gave an overview over Coupling mechanisms for Multi-Scale/Multi-Physics between the worlds of computer architectures, while Dr. Bernsdorf presented his current research activities in the are of medical Physics with a talk entiteled Towards Distributed Multi-Scale Simulation for Medical Physics Applications.